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lexA (LexA repressor)
FEATURES
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FAMILY
DESCRIPTION
Also known as LEXA_RHOPT, lexA. Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Homodimer.
Also known as LEXA_RHOPT, lexA. Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repa ... More
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lexA

LexA repressor

Molecular Synopsis