ibpA (Small heat shock protein IbpA)

FEATURES

FAMILY

DESCRIPTION

Also known as IBPA_ECOSM, ibpA. Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

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EXTERNAL LINKS

ibpA

Small heat shock protein IbpA

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

ibpA

Molecular Synopsis