FEATURES

FAMILY

DESCRIPTION

Also known as CFA20_CHLRE, CFAP20, BUG22, FAP20. Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (PubMed:24259666, PubMed:24574454). Involved in the control of flagellar beating in an asymmetric and planar waveform (PubMed:24259666, PubMed:24574454). Stabilizes outer doublet microtubules (DMTs) of the axoneme and may work as a scaffold for intratubular proteins, such as tektin and PACRG, to produce the beak structures in DMT1, 5 and 6 (PubMed:24259666, PubMed:24574454). Not essential for flagellar assembly (PubMed:24574454).

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EXTERNAL LINKS

CFAP20

Cilia- and flagella-associated protein 20

ligandability Mutations

Molecular Synopsis
Structural Ligandability

CFAP20

Structural Ligandability

Domains Chains

Distribution