hisF (Imidazole glycerol phosphate synthase subunit HisF)

FEATURES

FAMILY

DESCRIPTION

Also known as HIS6_CROS8, hisF. IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. Heterodimer of HisH and HisF.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

hisF

Imidazole glycerol phosphate synthase subunit HisF

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

hisF

Molecular Synopsis