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RIMBP3C (RIMS-binding protein 3C)
FEATURES
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FAMILY
DESCRIPTION
Also known as RIM3C_HUMAN, RIMBP3C. Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Interacts with LRGUK (via guanylate kinase-like domain). Interacts (via C-terminus) with HOOK1 (via coiled-coil region) (By similarity). May interact with FASLG (PubMed:19807924).
Also known as RIM3C_HUMAN, RIMBP3C. Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Interacts with LRGUK (via guanylate kinase-like domain). Interacts (via C-terminus) with HOOK1 (via coiled-coil region) (By similarity). May interact with ... More
RIMBP3C logo

RIMBP3C

RIMS-binding protein 3C

Copy number variation

DiseaseSignal Cell linesGain Cell linesAvg. ampLoss Cell linesAvg. lossNo-signal Cell linesAvg. change
adenocarcinoma 0 0 0 144 0.98
other 0 0 0 56 0.93
cancer 1 1 4.72 0 145 0.97
NS 2 2 2.53 0 150 0.96
carcinoma 9 8 2.56 1 0.45 540 0.96
haematopoietic_neoplasm 1 1 3.04 0 62 1.02
leukaemia 1 1 3.04 0 83 1.02
lymphoid_neoplasm 1 1 3.04 0 133 0.99
glioma 0 0 0 52 1.00
malignant_melanoma 0 0 0 56 1.10

Cell lines

Cell lineSignalCopy numberAvg. genome ploidyAmplificationDiseaseTissue
HCT-116 No signal 2 1.98 1.01 adenocarcinoma, other, cancer, NS, carcinoma colon, colorectal, large_intestine
TOV-21G No signal 2 2.02 0.99 cancer, carcinoma ovary
PC-3 No signal 3 4.27 0.70 adenocarcinoma, cancer, NS, carcinoma pancreas, prostate, lung
OVCAR-8 No signal 2 2.42 0.83 adenocarcinoma, cancer, carcinoma ovary
22Rv-1 No signal 2 2.04 0.98 cancer, NS, carcinoma prostate
5637 No signal 4 2.99 1.34 cancer, carcinoma bladder, urinary_tract
639-V No signal 3 2.41 1.25 cancer, carcinoma bladder, ureter, urinary_tract
647-V No signal 2 2.50 0.80 cancer, carcinoma bladder, urinary_tract
697 No signal 2 1.98 1.01 haematopoietic_neoplasm, leukaemia, lymphoid_neoplasm blood_bone_marrow, haematopoietic_and_lymphoid_tissue
769-P No signal 2 1.97 1.02 carcinoma kidney