ATP8 (ATP synthase protein 8)

FEATURES

FAMILY

DESCRIPTION

Also known as ATP8_VANPO, ATP8. Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.

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EXTERNAL LINKS

ATP8

ATP synthase protein 8

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

ATP8

Molecular Synopsis