FEATURES

FAMILY

DESCRIPTION

Also known as DEN11_HUMAN, DENND11, KIAA1147, LCHN. Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia (By similarity).

... More

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

DENND11

DENN domain-containing protein 11

ligandability Mutations

DENND11

Molecular Synopsis