FEATURES

FAMILY

DESCRIPTION

Also known as RUVB_SHELP, ruvB. The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. Forms a complex with RuvA.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

ruvB

Holliday junction ATP-dependent DNA helicase RuvB

ligandability Mutations

ruvB

Molecular Synopsis