No data available

FEATURES

FAMILY

alpha-IPM synthase/homocitrate synthase family

DESCRIPTION

Also known as LEU1_PROM0, leuA. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Homotetramer.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

leuA

2-isopropylmalate synthase

ligandability Mutations

Molecular Synopsis

Produced by the canSAR Team

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