FEATURES

DESCRIPTION

Also known as MNMC_BURP0, mnmC. Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

mnmC

tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC

ligandability Mutations

mnmC

Molecular Synopsis