menD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase)

FEATURES

FAMILY

DESCRIPTION

Also known as MEND_ACTP2, menD. Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Homodimer.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

menD

2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

menD

Molecular Synopsis