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BRE1A (E3 ubiquitin-protein ligase BRE1-like 1)
FEATURES
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FAMILY
DESCRIPTION
Also known as BRE1A_ORYSI, BRE1A. E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
Also known as BRE1A_ORYSI, BRE1A. E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in coopera ...
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BRE1A

E3 ubiquitin-protein ligase BRE1-like 1

Molecular Synopsis