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dphB (Diphthine synthase)
FEATURES
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FAMILY
DESCRIPTION
Also known as DPHB_METLZ, dphB. S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. Homodimer.
Also known as DPHB_METLZ, dphB. S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide bio ...
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dphB

Diphthine synthase

Molecular Synopsis