M5 (C2H2-type zinc-finger transcription factor M5)

FEATURES

FAMILY

GLI C2H2-type zinc-finger protein family

DESCRIPTION

Also known as MFM5_PHOSM, M5. Transcription factor that probably regulates the expression of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a lead compound for the treatment of hyper-cholesterolemia by targeting squalene synthase (SS).

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

M5

C2H2-type zinc-finger transcription factor M5

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

M5

Molecular Synopsis