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GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN NAV1.7(E406K) IN COMPLEX WITH AUXILIARY BETA SUBUNITS, HUWENTOXIN-IV AND SAXITOXIN (S6IV ALPHA HELIX CONFORMER)
DATE LAST MODIFIED
-
RELEASE
25 May 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
3
PUBMED ID
DOI
10.1016/J.CELREP.2022.110735
PDBe
--
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q15858 | SCN9A, NENA | HOMO SAPIENS | HUMAN | NEUROENDOCRINE SODIUM CHANNEL,HNE-NA,PERIPHERAL SO ... | Mutations | |
| Q07699 | SCN1B | HOMO SAPIENS | HUMAN | NAV1.7 BETA1 SUBUNIT | Mutations | |
| O60939 | SCN2B | HOMO SAPIENS | HUMAN | NAV1.7 BETA2 SUBUNIT | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402