7U9Y logo

7U9Y

3D Structure View

Loading...

More Info

GENERAL
TITLE
WDR5 BOUND TO 2-(3,5-DIMETHOXYBENZYL)-7-((2-METHYL-1H-IMIDAZOL-1-YL) METHYL)-5-(1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)-3,4- DIHYDROISOQUINOLIN-1(2H)-ONE
DATE LAST MODIFIED
11 May 2022
RELEASE
27 Apr 2022
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/TRANSCRIPTION INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.2C00195
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P61964 WDR5, BIG3 ESCHERICHIA COLI K-12 HUMAN
BMP2-INDUCED 3-KB GENE PROTEIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402