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GENERAL
TITLE
CRYSTAL STRUCTURE OF ALPN-202 (ENGINEERED CD80 VIGD) IN COMPLEX WITH PD-L1
DATE LAST MODIFIED
20 Apr 2022
RELEASE
16 Mar 2022
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.15
RESOLUTION RANGE LOW
95.38
PUBMED ID
DOI
10.1038/S41467-022-29286-5
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P33681 CD80, CD28LG, CD28LG1, LAB7 HOMO SAPIENS HUMAN
ACTIVATION B7-1 ANTIGEN,BB1,CTLA-4 COUNTER-RECEPTO ...
Mutations
Q9NZQ7 CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 HOMO SAPIENS HUMAN
PD-L1,PDCD1 LIGAND 1,PROGRAMMED DEATH LIGAND 1,HPD ...
Mutations
P33681 CD80, CD28LG, CD28LG1, LAB7 HOMO SAPIENS HUMAN
ACTIVATION B7-1 ANTIGEN,BB1,CTLA-4 COUNTER-RECEPTO ...
Mutations
Q9NZQ7 CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 HOMO SAPIENS HUMAN
PD-L1,PDCD1 LIGAND 1,PROGRAMMED DEATH LIGAND 1,HPD ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402