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GENERAL
TITLE
CRYSTAL STRUCTURE OF SMALL MOLECULE BETA-LACTONE 5 COVALENTLY BOUND TO K-RAS(G12S)
DATE LAST MODIFIED
10 Aug 2022
RELEASE
3 Aug 2022
OBSOLETE
CLASSIFICATION
ONCOPROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
66.53
PUBMED ID
DOI
10.1038/S41589-022-01065-9
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402