7T9N logo

7T9N

3D Structure View

Loading...

More Info

GENERAL
TITLE
M22 AGONIST AUTOANTIBODY BOUND TO HUMAN THYROTROPIN RECEPTOR IN COMPLEX WITH MINIGS399 (COMPOSITE STRUCTURE)
DATE LAST MODIFIED
24 Aug 2022
RELEASE
3 Aug 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
2.9
PUBMED ID
DOI
10.1038/S41586-022-05159-1
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
-- TRICHOPLUSIA NI HUMAN --
P0DOY3 -- TRICHOPLUSIA NI HUMAN --
-- ESCHERICHIA COLI HUMAN --
TSHR HOMO SAPIENS HUMAN --
P63092 GNAS, GNAS1, GSP HOMO SAPIENS HUMAN
ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN
Mutations
P62873 GNB1 TRICHOPLUSIA NI HUMAN
TRANSDUCIN BETA CHAIN 1
Mutations
P59768 GNG2 TRICHOPLUSIA NI HUMAN
G GAMMA-I
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402