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GENERAL
TITLE
CRYSTAL STRUCTURE OF HIV-1 K103N, Y181C MUTANT REVERSE TRANSCRIPTASE IN COMPLEX WITH 5-(2-(2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL) ETHOXY)PHENOXY)-7-FLUORO-2-NAPHTHONITRILE (JLJ635), A NON-NUCLEOSIDE INHIBITOR
DATE LAST MODIFIED
-
RELEASE
16 Mar 2022
OBSOLETE
CLASSIFICATION
TRANSFERASE, VIRAL PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.79
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.3389/FMOLB.2022.805187
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03366 GAG-POL ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M
PR160GAG-POL
Mutations
P03366 GAG-POL ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' HIV-1 -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402