7SII

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7SII_1

Chain 7SII_A

Chain 7SII_B

Chain 7SII_C

Chain 7SII_D

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GENERAL

TITLE

HUMAN STING BOUND TO BOTH CGAMP AND 1-[(2-CHLORO-6-FLUOROPHENYL) METHYL]-3,3-DIMETHYL-2-OXO-N-[(2,4,6-TRIFLUOROPHENYL)METHYL]-2,3- DIHYDRO-1H-INDOLE-6-CARBOXAMIDE (COMPOUND 53)

DATE LAST MODIFIED

4 May 2022

RELEASE

2 Feb 2022

OBSOLETE

CLASSIFICATION

IMMUNE SYSTEM

EXPERIMENT TYPE

ELECTRON MICROSCOPY

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

3.45

RESOLUTION RANGE LOW

3.45

PUBMED ID

35388221

DOI

10.1038/S41586-022-04559-7

PDBe

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q86WV6	STING1, ERIS, MITA, TMEM173	HOMO SAPIENS	HUMAN	HSTING,ENDOPLASMIC RETICULUM INTERFERON STIMULATOR ...	Mutations
Q86WV6	STING1, ERIS, MITA, TMEM173	HOMO SAPIENS	HUMAN	HSTING,ENDOPLASMIC RETICULUM INTERFERON STIMULATOR ...	Mutations
Q86WV6	STING1, ERIS, MITA, TMEM173	HOMO SAPIENS	HUMAN	HSTING,ENDOPLASMIC RETICULUM INTERFERON STIMULATOR ...	Mutations
Q86WV6	STING1, ERIS, MITA, TMEM173	HOMO SAPIENS	HUMAN	HSTING,ENDOPLASMIC RETICULUM INTERFERON STIMULATOR ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402