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GENERAL
TITLE
DISCOVERY OF AN ANION-DEPENDENT FARNESYLTRANSFERASE INHIBITOR FROM A PHENOTYPIC SCREEN
DATE LAST MODIFIED
-
RELEASE
8 Sept 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61
RESOLUTION RANGE HIGH
2.28
RESOLUTION RANGE LOW
34
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.0C00551
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q04631 FNTA ESCHERICHIA COLI RAT
CAAX FARNESYLTRANSFERASE SUBUNIT ALPHA,FTASE-ALPHA ...
Mutations
P49356 FNTB ESCHERICHIA COLI RAT
FTASE-BETA,CAAX FARNESYLTRANSFERASE SUBUNIT BETA,R ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402