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GENERAL
TITLE
CRYSTAL STRUCTURE OF A MUTANT (P393GX) THYROID RECEPTOR ALPHA LIGAND BINDING DOMAIN DESIGNED TO MODEL DOMINANT NEGATIVE HUMAN MUTATIONS.
DATE LAST MODIFIED
2 Mar 2022
RELEASE
26 Jan 2022
OBSOLETE
CLASSIFICATION
NUCLEAR PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64 2 2
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
72.06
PUBMED ID
DOI
10.1128/MCB.00363-21
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P10827 THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2 ESCHERICHIA COLI HUMAN
NUCLEAR RECEPTOR SUBFAMILY 1 GROUP A MEMBER 1,V-ER ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402