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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN CDK12/CYCLIN K IN COMPLEX WITH THE INHIBITOR BSJ-01-175
DATE LAST MODIFIED
-
RELEASE
12 May 2021
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
49
PUBMED ID
DOI
10.1016/J.EJMECH.2021.113481
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q9NYV4 CDK12, CRK7, CRKRS, KIAA0904 SPODOPTERA FRUGIPERDA HUMAN
CDC2-RELATED KINASE,ARGININE/SERINE-RICH,CRKRS,CEL ...
Mutations
O75909 CCNK, CPR4 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
Q9NYV4 CDK12, CRK7, CRKRS, KIAA0904 SPODOPTERA FRUGIPERDA HUMAN
CDC2-RELATED KINASE,ARGININE/SERINE-RICH,CRKRS,CEL ...
Mutations
O75909 CCNK, CPR4 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402