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GENERAL
TITLE
HUMAN MEDIATOR WITH RNA POLYMERASE II PRE-INITIATION COMPLEX
DATE LAST MODIFIED
16 Jun 2021
RELEASE
5 May 2021
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
4.5
RESOLUTION RANGE LOW
4.5
PUBMED ID
DOI
10.1038/S41586-021-03554-8
PDBe
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LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P18074 ERCC2, XPD, XPDC TRICHOPLUSIA NI HUMAN
BASIC TRANSCRIPTION FACTOR 2 80 KDA SUBUNIT,BTF2 P ...
Mutations
P32780 GTF2H1, BTF2 TRICHOPLUSIA NI HUMAN
BASIC TRANSCRIPTION FACTOR 2 62 KDA SUBUNIT,BTF2 P ...
Mutations
Q92759 GTF2H4 TRICHOPLUSIA NI HUMAN
BASIC TRANSCRIPTION FACTOR 2 52 KDA SUBUNIT,BTF2 P ...
Mutations
P51948 MNAT1, CAP35, MAT1, RNF66 TRICHOPLUSIA NI HUMAN
CDK7/CYCLIN-H ASSEMBLY FACTOR,CYCLIN-G1-INTERACTIN ...
Mutations
Q13889 GTF2H3 TRICHOPLUSIA NI HUMAN
BASIC TRANSCRIPTION FACTOR 2 34 KDA SUBUNIT,BTF2 P ...
Mutations
Q6ZYL4 GTF2H5, C6ORF175, TTDA TRICHOPLUSIA NI HUMAN
GENERAL TRANSCRIPTION FACTOR IIH POLYPEPTIDE 5,TFB ...
Mutations
Q13888 GTF2H2, BTF2P44 TRICHOPLUSIA NI HUMAN
BASIC TRANSCRIPTION FACTOR 2 44 KDA SUBUNIT,BTF2 P ...
Mutations
P19447 ERCC3, XPB, XPBC TRICHOPLUSIA NI HUMAN
TFIIH SUBUNIT XPB,BASIC TRANSCRIPTION FACTOR 2 89 ...
Mutations
P50613 CDK7, CAK, CAK1, CDKN7, MO15, STK1 TRICHOPLUSIA NI HUMAN
39 KDA PROTEIN KINASE,P39 MO15,CDK-ACTIVATING KINA ...
Mutations
P51946 CCNH TRICHOPLUSIA NI HUMAN
MO15-ASSOCIATED PROTEIN,P34,P37
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402