7ND1

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7ND1_1

Chain 7ND1_A

Chain 7ND1_H

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GENERAL

TITLE

FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1) RING DOMAIN

DATE LAST MODIFIED

7 Jul 2021

RELEASE

16 Jun 2021

OBSOLETE

CLASSIFICATION

GENE REGULATION

EXPERIMENT TYPE

NMR

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/S41589-021-00815-5

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q99496	RNF2, BAP1, DING, HIPI3, RING1B	ESCHERICHIA COLI	HUMAN	HUNTINGTIN-INTERACTING PROTEIN 2-INTERACTING PROTE ...	Mutations
	P35226	BMI1, PCGF4, RNF51	ESCHERICHIA COLI	HUMAN	POLYCOMB GROUP RING FINGER PROTEIN 4,RING FINGER P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402