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GENERAL
TITLE
STRUCTURE OF GDF11 BOUND TO FUSED ACTRIIB-ECD AND ALK4-ECD WITH ANTI- ACTRIIB FAB FRAGMENT
DATE LAST MODIFIED
-
RELEASE
19 Jan 2022
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
49.51
PUBMED ID
DOI
10.1016/J.ISCI.2021.103590
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O95390 GDF11, BMP11 CRICETULUS GRISEUS HUMAN
GDF-11,BONE MORPHOGENETIC PROTEIN 11,BMP-11
Mutations
P36896 ACVR2B, ACVR1B, ACVRLK4, ALK4 CRICETULUS GRISEUS HUMAN
ACTR-IIB FUSED TO ACTIVIN RECEPTOR-LIKE KINASE 4
Mutations
P01824 -- CRICETULUS GRISEUS HOMO SAPIENS --
P06312 -- CRICETULUS GRISEUS HOMO SAPIENS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402