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GENERAL
TITLE
STRUCTURE OF THE HER2/HER3/NRG1B HETERODIMER EXTRACELLULAR DOMAIN BOUND TO TRASTUZUMAB FAB
DATE LAST MODIFIED
22 Dec 2021
RELEASE
10 Nov 2021
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/IMMUNE SYSTEM
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.45
RESOLUTION RANGE LOW
3.45
PUBMED ID
DOI
10.1038/S41586-021-04084-Z
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P21860 ERBB3, HER3 HOMO SAPIENS HUMAN
PROTO-ONCOGENE-LIKE PROTEIN C-ERBB-3,TYROSINE KINA ...
Mutations
P04626 ERBB2, HER2, MLN19, NEU, NGL, MALE, B4034, JW3994 HOMO SAPIENS HUMAN
TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER2,MB ...
Mutations
-- HOMO SAPIENS HOMO SAPIENS --
-- HOMO SAPIENS HOMO SAPIENS --
Q02297 NRG1, GGF, HGL, HRGA, NDF, SMDF ESCHERICHIA COLI HUMAN
PRO-NRG1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402