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GENERAL
TITLE
DIMERIC (BRAF)2:(14-3-3)2 COMPLEX BOUND TO SB590885 INHIBITOR
DATE LAST MODIFIED
9 Feb 2022
RELEASE
26 Jan 2022
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.89
RESOLUTION RANGE LOW
3.89
PUBMED ID
DOI
10.1038/S41467-022-28084-3
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P15056 BRAF, BRAF1, RAFB1 HOMO SAPIENS HUMAN
PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
Mutations
P15056 BRAF, BRAF1, RAFB1 HOMO SAPIENS HUMAN
PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
Mutations
P63104 -- HOMO SAPIENS HUMAN
PROTEIN KINASE C INHIBITOR PROTEIN 1,KCIP-1
Mutations
P63104 -- HOMO SAPIENS HUMAN
PROTEIN KINASE C INHIBITOR PROTEIN 1,KCIP-1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402