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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH 2-{(7P)-7-(1,4-DIMETHYL-1H-1,2,3-TRIAZOL-5-YL)-8-FLUORO-5-[(S)- (OXAN-4-YL)(PHENYL)METHYL]-5H-PYRIDO[3,2-B]INDOL-3-YL}PROPAN-2-OL
DATE LAST MODIFIED
-
RELEASE
29 Sept 2021
OBSOLETE
CLASSIFICATION
CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
1.76
RESOLUTION RANGE LOW
50
PUBMED ID
-
DOI
10.1016/J.BMCL.2021.128376
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O60885 BRD4, HUNK1 ESCHERICHIA COLI BL21(DE3) HUMAN
PROTEIN HUNK1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402