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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE HUMAN ADENOSINE A1 RECEPTOR-GI2-PROTEIN COMPLEX BOUND TO ITS ENDOGENOUS AGONIST AND AN ALLOSTERIC LIGAND
DATE LAST MODIFIED
13 Oct 2021
RELEASE
8 Sept 2021
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
3.2
PUBMED ID
DOI
10.1038/S41586-021-03897-2
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P04899 GNAI2, GNAI2B TRICHOPLUSIA NI HUMAN
ADENYLATE CYCLASE-INHIBITING G ALPHA PROTEIN
Mutations
P62873 GNB1 TRICHOPLUSIA NI HUMAN
TRANSDUCIN BETA CHAIN 1
Mutations
P59768 GNG2 TRICHOPLUSIA NI HUMAN
G GAMMA-I
Mutations
P30542 CHRM4, ADORA1 TRICHOPLUSIA NI HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402