7KYV logo

7KYV

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM634 (3-METHYL-N-(1-(5- METHYLISOXAZOL-3-YL)ETHYL)-4-(4-(TRIFLUOROMETHYL)BENZYL)-1H-PYRROLE- 2-CARBOXAMIDE)
DATE LAST MODIFIED
8 Dec 2021
RELEASE
19 May 2021
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
42.64
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C00173
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q08210 PFF0160C ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7)
DHODEHASE,DIHYDROOROTATE OXIDASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402