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3D Structure View

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GENERAL
TITLE
WILD-TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH METHOTREXATE (MTX), NADPH AND DUMP
DATE LAST MODIFIED
23 Mar 2022
RELEASE
22 Sept 2021
OBSOLETE
CLASSIFICATION
STRUCTURAL PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.25
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.STR.2021.09.004

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P13922 DHFR-TS, DHFR-TS ESCHERICHIA COLI MALARIA PARASITE P. FALCIPARUM -- Mutations
P13922 DHFR-TS, DHFR-TS ESCHERICHIA COLI MALARIA PARASITE P. FALCIPARUM -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402