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GENERAL
TITLE
CRYSTAL STRUCTURE OF PDE4D CATALYTIC DOMAIN IN COMPLEX WITH APREMILAST
DATE LAST MODIFIED
10 Feb 2021
RELEASE
27 Jan 2021
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.58
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.EJMECH.2020.113004
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q08499 PDE4D, DPDE3 ESCHERICHIA COLI BL21(DE3) HUMAN
PDE4D, DPDE3, PDE43
Mutations
Q08499 PDE4D, DPDE3 ESCHERICHIA COLI BL21(DE3) HUMAN
PDE4D, DPDE3, PDE43
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402