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GENERAL
TITLE
THE CRYSTAL STRUCTURE OF MLL2 IN COMPLEX WITH ASH2L AND RBBP5
DATE LAST MODIFIED
21 Oct 2020
RELEASE
22 Jul 2020
OBSOLETE
CLASSIFICATION
PROTEIN BINDING
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.STR.2020.07.002
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q9UBL3 ASH2L, ASH2L1 ESCHERICHIA COLI BL21(DE3) HUMAN
ASH2-LIKE PROTEIN
Mutations
Q9UMN6 MLL2 ESCHERICHIA COLI BL21(DE3) HUMAN
LYSINE N-METHYLTRANSFERASE 2B,MYELOID/LYMPHOID OR ...
Mutations
Q15291 RBBP5 ESCHERICHIA COLI BL21(DE3) HUMAN
RBBP-5,RETINOBLASTOMA-BINDING PROTEIN RBQ-3
Mutations
Q9UBL3 ASH2L, ASH2L1 ESCHERICHIA COLI BL21(DE3) HUMAN
ASH2-LIKE PROTEIN
Mutations
Q9UMN6 MLL2 ESCHERICHIA COLI BL21(DE3) HUMAN
LYSINE N-METHYLTRANSFERASE 2B,MYELOID/LYMPHOID OR ...
Mutations
Q15291 RBBP5 ESCHERICHIA COLI BL21(DE3) HUMAN
RBBP-5,RETINOBLASTOMA-BINDING PROTEIN RBQ-3
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402