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GENERAL
TITLE
CRYSTAL STRUCTURE OF AURORA A IN COMPLEX WITH 7-(2-ANILINOPYRIMIDIN-4- YL)-1-BENZAZEPIN-2-ONE DERIVATIVE (COMPOUND 2A)
DATE LAST MODIFIED
14 Apr 2021
RELEASE
13 Jan 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.86
RESOLUTION RANGE LOW
44.43
PUBMED ID
DOI
10.3390/MOLECULES26061611
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O14965 AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6 ESCHERICHIA COLI BL21(DE3) HUMAN
AURORA 2,AURORA/IPL1-RELATED KINASE 1,HARK1,BREAST ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402