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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIFTH BROMODOMAIN OF HUMAN PROTEIN POLYBROMO- 1 IN COMPLEX WITH 2-(6-AMINO-5-(PIPERAZIN-1-YL)PYRIDAZIN-3-YL)PHENOL
DATE LAST MODIFIED
5 May 2021
RELEASE
7 Oct 2020
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
1.67
RESOLUTION RANGE LOW
53.6
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.0C01242
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q86U86 PBRM1, BAF180, PB1 ESCHERICHIA COLI HUMAN
HPB1,BRG1-ASSOCIATED FACTOR 180,BAF180,POLYBROMO-1 ...
Mutations
Q86U86 PBRM1, BAF180, PB1 ESCHERICHIA COLI HUMAN
HPB1,BRG1-ASSOCIATED FACTOR 180,BAF180,POLYBROMO-1 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402