6ZJZ logo

6ZJZ

3D Structure View

Loading...

More Info

GENERAL
TITLE
DISCOVERY OF M5049: A NOVEL SELECTIVE TLR7/8 INHIBITOR FOR TREATMENT OF AUTOIMMUNITY
DATE LAST MODIFIED
3 Mar 2021
RELEASE
30 Dec 2020
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.489
RESOLUTION RANGE LOW
135.87
PUBMED ID
DOI
10.1124/JPET.120.000275
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q9NR97 TLR8, UNQ249/PRO286 DROSOPHILA FALLENI HUMAN -- Mutations
Q9NR97 TLR8, UNQ249/PRO286 DROSOPHILA FALLENI HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402