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GENERAL
TITLE
CRYSTAL STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE (PKA) IN COMPLEX WITH THE METHYLATED FASUDIL-DERIVED FRAGMENT N-METHYLISOQUINOLINE-5- SULFONAMIDE (SOAKED)
DATE LAST MODIFIED
20 Jan 2021
RELEASE
14 Oct 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.396
RESOLUTION RANGE LOW
45.577
PUBMED ID
DOI
10.1002/CMDC.202000565

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P17612 PRKACA ESCHERICHIA COLI BL21(DE3) CHINESE HAMSTER
PKA C-ALPHA
P63248 -- -- HOUSE MOUSE
PKI-ALPHA,CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402