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GENERAL
TITLE
CRYSTAL STRUCTURE OF MKK7 (MAP2K7) COVALENTLY BOUND WITH TYPE-II INHIBITOR SB1-G-23
DATE LAST MODIFIED
28 Oct 2020
RELEASE
12 Aug 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
61.83
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2020.07.014
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O14733 MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4 ESCHERICHIA COLI BL21(DE3) HUMAN
MAPKK 7,JNK-ACTIVATING KINASE 2,MAPK/ERK KINASE 7, ...
Mutations
O14733 MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4 ESCHERICHIA COLI BL21(DE3) HUMAN
MAPKK 7,JNK-ACTIVATING KINASE 2,MAPK/ERK KINASE 7, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402