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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PHENYLETHANOLAMINE N-METHYLTRANSFERASE (PNMT) IN COMPLEX WITH (2S)-2-AMINO-4-((((2R,5R)-5-(6-AMINO-9H-PURIN- 9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL)(3-(7,8-DICHLORO-1,2, 3,4-TETRAHYDROISOQUINOLIN-4-YL)PROPYL)AMINO)BUTANOIC ACID AND ADOHCY (SAH)
DATE LAST MODIFIED
2 Sept 2020
RELEASE
5 Aug 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
2.76
RESOLUTION RANGE LOW
94.14
PUBMED ID
DOI
10.1021/JACS.0C05446

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11086 PNMT, PENT ESCHERICHIA COLI HUMAN
PNMTASE,NORADRENALINE N-METHYLTRANSFERASE
Mutations
P11086 PNMT, PENT ESCHERICHIA COLI HUMAN
PNMTASE,NORADRENALINE N-METHYLTRANSFERASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402