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GENERAL
TITLE
QUATERNARY COMPLEX OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH FLAVIN MONONUCLEOTIDE (FMN), OROTIC ACID AND AG-636
DATE LAST MODIFIED
16 Dec 2020
RELEASE
4 Nov 2020
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
1.97
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1158/1535-7163.MCT-20-0550

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q02127 DHODH ESCHERICHIA COLI HUMAN
DHODEHASE,DIHYDROOROTATE OXIDASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402