6VHG logo

6VHG

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN COMPLEXED WITH A PYRAZOLO[1,5-A]PYRIMIDINE INHIBITOR
DATE LAST MODIFIED
29 Apr 2020
RELEASE
26 Feb 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 63 2 2
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
41
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.0C00015

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07949 RET, CDHF12, CDHR16, PTC, RET51 SPODOPTERA FRUGIPERDA HUMAN
CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402