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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE BRAF:MEK1 KINASES IN COMPLEX WITH AMPPNP AND PIMASERTIB
DATE LAST MODIFIED
-
RELEASE
2 Dec 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
3.09
RESOLUTION RANGE LOW
43.552
PUBMED ID
-
DOI
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P15056 BRAF, BRAF1, RAFB1 SPODOPTERA FRUGIPERDA HUMAN
PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
Mutations
Q02750 MAP2K1, MEK1, PRKMK1 SPODOPTERA FRUGIPERDA HUMAN
MKK1,ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1,MEK ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402