6U25 logo

6U25

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS- RORGT(244- 487)-L6-SRC1(678-692)) IN COMPLEX WITH A TRICYCLIC INVERSE AGONIST
DATE LAST MODIFIED
27 Nov 2019
RELEASE
6 Nov 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2.61
RESOLUTION RANGE LOW
158.27
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01369
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P51449 RORC, NR1F3, RORG, RZRG, NCOA1, BHLHE74, SRC1 ESCHERICHIA COLI HUMAN
NUCLEAR RECEPTOR RZR-GAMMA,STEROID RECEPTOR COACTI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402