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6TE1

3D Structure View

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GENERAL
TITLE
STRUCTURE OF THE KDM1A/COREST COMPLEX WITH THE INHIBITOR 2-[3-{4- CHLORO-3-[(4-CHLOROPHENYL)ETHYNYL]PHENYL}-1-(3-MORPHOLIN-4-YLPROPYL)- 1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]-2-OXOETHANOL
DATE LAST MODIFIED
-
RELEASE
3 Jun 2020
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
3.11
RESOLUTION RANGE LOW
46.23
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.9B00604

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O60341 KDM1A, AOF2, KDM1, KIAA0601, LSD1 ESCHERICHIA COLI HUMAN
BRAF35-HDAC COMPLEX PROTEIN BHC110,FLAVIN-CONTAINI ...
Mutations
Q9UKL0 RCOR1, KIAA0071, RCOR ESCHERICHIA COLI HUMAN
PROTEIN COREST
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402