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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 6 (N217D/I218Y/K224R) IN COMPLEX WITH GSK3496783A
DATE LAST MODIFIED
2 Oct 2019
RELEASE
25 Sept 2019
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.84
RESOLUTION RANGE LOW
46.11
PUBMED ID
DOI
10.1016/J.BMCL.2019.126675
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q92876 KLK6, PRSS18, PRSS9 BACULOVIRUS EXPRESSION VECTOR PFASTBAC1-HM HUMAN
NEUROSIN,PROTEASE M,SP59,SERINE PROTEASE 18,SERINE ...
Mutations
Q92876 KLK6, PRSS18, PRSS9 BACULOVIRUS EXPRESSION VECTOR PFASTBAC1-HM HUMAN
NEUROSIN,PROTEASE M,SP59,SERINE PROTEASE 18,SERINE ...
Mutations
Q92876 KLK6, PRSS18, PRSS9 BACULOVIRUS EXPRESSION VECTOR PFASTBAC1-HM HUMAN
NEUROSIN,PROTEASE M,SP59,SERINE PROTEASE 18,SERINE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402