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GENERAL
TITLE
STRUCTURE OF RET PROTEIN TYROSINE KINASE DOMAIN IN COMPLEX WITH NINTEDANIB
DATE LAST MODIFIED
18 Dec 2019
RELEASE
5 Jun 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.87
RESOLUTION RANGE LOW
78.6
PUBMED ID
DOI
10.1074/JBC.RA119.007682
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07949 RET, CDHF12, CDHR16, PTC, RET51 SPODOPTERA FRUGIPERDA HUMAN
CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
Mutations
P07949 RET, CDHF12, CDHR16, PTC, RET51 SPODOPTERA FRUGIPERDA HUMAN
CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402