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GENERAL
TITLE
CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A NOTCH FRAGMENT
DATE LAST MODIFIED
29 Jul 2020
RELEASE
26 Dec 2018
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.7
RESOLUTION RANGE LOW
2.7
PUBMED ID
DOI
10.1038/S41586-018-0813-8
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q92542 NCSTN HOMO SAPIENS HUMAN -- Mutations
P49768 PS1 HOMO SAPIENS HUMAN
PS-1
Mutations
Q96BI3 APH1A HOMO SAPIENS HUMAN
APH-1A
Mutations
Q9NZ42 PEN2 HOMO SAPIENS HUMAN
PRESENILIN ENHANCER PROTEIN 2
Mutations
P46531 -- HOMO SAPIENS HOMO SAPIENS -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402