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TITLE
STRUCTURE OF CDK12/CYCK IN COMPLEX WITH A SMALL MOLECULE INHIBITOR N- (4-(1-METHYL-1H-PYRAZOL-4-YL)PHENYL)-N-((1R,4R)-4-(QUINAZOLIN-2- YLAMINO)CYCLOHEXYL)ACETAMIDE
EXPRESSION SYSTEM(S)
UNIDENTIFIED BACULOVIRUS ,
EXPERIMENT TYPE
X-RAY DIFFRACTION
ORGANISM(S)
HOMO SAPIENS ,
CLASSIFICATION
TRANSFERASE/INHIBITOR
SPACE GROUP:
P 21 21 21
RESOLUTION RANGE HIGH:
2.75
RESOLUTION RANGE LOW:
50
DOI:
10.1021/ACS.JMEDCHEM.8B00683
EM DATA RESOURCE:
[]
DATE DEPOSITED:
--
DATE RELEASED:
--
DATE REVISED:
--
BIOLOGICAL ASSEMBLY:
[]
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3D Structure - 6CKX

3D Viewer

6CKX_D
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganism CommonSynonims
6CKX_D O75909 CCNK, CPR4 UNIDENTIFIED BACULOVIRUS HUMAN --
6CKX_C Q9NYV4 CDK12, CRK7, CRKRS, KIAA0904 UNIDENTIFIED BACULOVIRUS HUMAN CDC2-RELATED KINASE,ARGININE/SERINE-RICH,CRKRS,CELL DIVISIONCYCLE 2-RELATED PROTEIN KINASE 7,CDC2-RELATED PROTEIN KINASE 7,CELLDIVISION PROTEIN KINASE 12,HCDK12
6CKX_B O75909 CCNK, CPR4 UNIDENTIFIED BACULOVIRUS HUMAN --
6CKX_A Q9NYV4 CDK12, CRK7, CRKRS, KIAA0904 UNIDENTIFIED BACULOVIRUS HUMAN CDC2-RELATED KINASE,ARGININE/SERINE-RICH,CRKRS,CELL DIVISIONCYCLE 2-RELATED PROTEIN KINASE 7,CDC2-RELATED PROTEIN KINASE 7,CELLDIVISION PROTEIN KINASE 12,HCDK12